50606-32-1, Butyl piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
50606-32-1, Example 33: (lalpha,5alpha,6beta)-3-{6-[2-(4-Butoxycarbonyl-piperazin-l-yl)-2-oxo- ethylcarbamoyl]-2-phenyl-pyrimidin-4-yl}-3-aza-bicyclo[3.1.0]hexane-6-carboxylic acid:33.1 4-(2-tert-Butoxycarbonylamino-acetyl)-piperazine-l-carboxylic acid butyl ester:To a solution of Boc-Glycine (2351 mg) in DCM (150 mL) were added HOBT hydrate (2358 mg) and EDCI hydrochloride (3100 mg) and the mixture was stirred for 30 min at RT. Intermediate 1.4 (2500 mg) was then added and the reaction mixture was stirred at RT overnight. A IN NaHStheta4 aqueous solution was added to the mixture, the formed solid was filtered off and the 2 phases of the filtrate were separated. The org. phase was washed with sat. Na2CO3 solution, dried (MgSO^ and evaporated off to afford 4620 mg of the desired compound as white solid. LC-MS: tR = 0.92 min; [M+H]+: 344.27.
As the paragraph descriping shows that 50606-32-1 is playing an increasingly important role.
Reference£º
Patent; ACTELION PHARMACEUTICALS LTD; CAROFF, Eva; HILPERT, Kurt; HUBLER, Francis; MEYER, Emmanuel; RENNEBERG, Dorte; WO2010/116328; (2010); A2;,
Piperazine – Wikipedia
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