76003-29-7, 1-Boc-3-Oxopiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
[005961 To a stirring solution of 1 -bromo-4-(heptyloxy)benzene (447 mg. 1.65 nunol) in dioxane (5 niL) were added tert-butyl 3-oxopiperazine-1-carboxylate (330 mg, 1.65 mmol), copper I iodide (31.4 mg, 0.17 mmol), (1R,2R)-Nl .N2-dimethylcyclohexane- 1,2- diarnine (234 mg. 1.65 nmiol) and potassium carbonate (456 rng, 3.30 mmol). The reaction mixture was heated at 120C for 16 h. The reaction mixture was passed through a plug of celite, eluted with EA (50 mL). The organics were washed with ammonium chloride (25 niL), water (25 niL) and brine (25 mL) then dried over MgSO4 and concentrated to afford 602 mg (89%) of tert-butyl 4-(4-(heptyloxy)phenyl)-3- oxopiperazine-l-carboxylate. LCMS-ESI (m/z) calculated for C22H34N204: 390.5; found 319.0 [M+Hf. 1R= 2.90 mi (i1vlethod4).
76003-29-7, The synthetic route of 76003-29-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; CELGENE INTERNATIONAL II SARL; BOEHM, Marcus, F.; MARTINBOROUGH, Esther; MOORJANI, Manisha; TAMIYA, Junko; HUANG, Liming; YEAGER, Adam, R.; BRAHMACHARY, Enugurthi; FOWLER, Thomas; NOVAK, Andrew; MEGHANI, Premji; KNAGGS, Michael; GLYNN, Daniel; MILLS, Mark; (851 pag.)WO2016/94729; (2016); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics