74879-18-8, (S)-(+)-2-Methylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
74879-18-8, Triethylamine (2.85 ml) was added to a solution of (S)-2-methyl piperazine (1 g) in methanol (25 ml), this was followed by portionwise addition of BOC anhydride (2.18 g). The reaction mixture was stirred for 17 h, then concentrated under reduced pressure. Water was added to the residue and extracted EtOAc (¡Á3), dried (MgSO4) and evaporated under reduced pressure. The residue was purified by chromatography on silica (eluent EtOAc, then 9:1:1 EtOAc:MeOH:NH3) to give the sub-title compound as a colourless oil, yield 1.3 g.1H NMR CDCl3: delta 4.04-3.82 (2H, m), 2.95 (1H, d), 2.81-2.66 (3H, m), 2.48-2.32 (1H, m), 1.47 (9H, s), 1.05 (3H, d).
As the paragraph descriping shows that 74879-18-8 is playing an increasingly important role.
Reference£º
Patent; ASTRAZENECA AB; US2008/255150; (2008); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics