Downstream synthetic route of 216144-45-5

216144-45-5, The synthetic route of 216144-45-5 has been constantly updated, and we look forward to future research findings.

216144-45-5, 4-(4-Methylpiperazin-1-yl)benzylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 2806-(2 , 3-dimethylphenyl)-4-N-{[4-(4-methylpi perazin-1 -yl)phenyl]methyl}pyrim idine2,4-diamine.A mixture of 4-chloro-6-(2,3-dimethylphenyl)pyrimidin-2-amine (23 mg, 0.10mmol), [4-(4-methylpiperazin-1-yl)phenyl]methanamine (29 mg, 0.14 mmol) andHunig?s base (35 pL, 0.20 mmol) in n-butanol (1.5 mL) was heated in a sealed tube at 85C overnight. The reaction mixture was concentrated and purified by preparative H PLC. LCMS [M+H] 403.

216144-45-5, The synthetic route of 216144-45-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; THOMAS HELLEDAYS STIFTELSE FOeR MEDICINSK FORSKNING; SCOBIE, Martin; HELLEDAY, Thomas; KOOLMEISTER, Tobias; JACQUES, Sylvain; DESROSES, Matthieu; JACQUES-CORDONNIER, Marie-Caroline; WO2014/84778; (2014); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics