120737-78-2, tert-Butyl 2-methylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 7-bromo-4,6-dichloro-8-fluoroquinazoline (2.4 g, 8.25 mmol) in dichloromethane (25 mL) at RT, tert-butyl 2-methylpiperazine-1-carboxylate (3.3 g, 16.5 mmol) and Et3N (5.3 g, 41.25 mmol) was added. The resulting mixture was stirred at RT for 40 min. The mixture was extracted with dichloromethane. The organic layer was washed with 1N HCl, water, saturated NaHCO3 solution and brine. The organic dried over Na2SO4 and concentrated. The residue was washed with mixture of petroleum ether/ ethyl acetate = 5:1 to afford the desired product as a white solid (2.8 g, 74 % yield)., 120737-78-2
As the paragraph descriping shows that 120737-78-2 is playing an increasingly important role.
Reference£º
Patent; ARAXES PHARMA LLC; LI, Liansheng; FENG, Jun; LONG, Yun Oliver; LIU, Yuan; WU, Tao; REN, Pingda; LIU, Yi; (335 pag.)WO2016/164675; (2016); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics