Analyzing the synthesis route of 31166-44-6

The synthetic route of 31166-44-6 has been constantly updated, and we look forward to future research findings.

31166-44-6, 1-Cbz-Piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 1-Cbz piperazine (1 g, 4.55 mmol),2-bromo-2-methylpropionamide (751 mg, 4.55 mmol),potassium carbonate (942 mg, 6.83 mmol) and acetonitrile (10 mE) was stirred at 80¡ã C. overnight. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel colunm chromatography to obtain 57-c (1.05 g, 76percent). EC-MS (ESI): mlz 306.3 (M+H)., 31166-44-6

The synthetic route of 31166-44-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SHANGHAI YINGLI PHARMACEUTICAL CO., LTD; XU, Zusheng; (174 pag.)US2016/214994; (2016); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics