Downstream synthetic route of 197638-83-8

197638-83-8, The synthetic route of 197638-83-8 has been constantly updated, and we look forward to future research findings.

197638-83-8, 1-Boc-4-(4-Formylphenyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

tert-Butyl 4-[4-((hydroxyimino)methyl)phenyl]piperazinecarboxylate (Compound 32) A mixture of aldehyde 28 (10 mmol) and hydroxylamine hydrochloride (15 mmol) in MeOH (20 mL) with pyridine (2 mL) is stirred at r.t. for 12-15 h. The solvent is removed under vacuum, and the residue is distributed between EtOAc (100 mL) and water (30 mL). The organic layer is washed with 2% aq. citric acid (2*30 mL), water (30 mL), brine (30 mL), and dried (MgSO4). The solvent is evaporated and Compound 32 dried under vacuum.

197638-83-8, The synthetic route of 197638-83-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Gordeev, Mikhail F.; Patel, Dinesh V.; Barbachyn, Michael R.; Gage, James R.; US2003/13737; (2003); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics