373608-48-1, tert-Butyl 4-(3-aminopropyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Tert-butyl 4-(3-((2,4-dinitrophenyl)amino)propyl)piperazine-l-carboxylateTo a stirred solution of tert-butyl 4-(3-aminopropyl)piperazine-l-carboxylate (2 g, 8.22 mmol), in dichloromethane (DCM) (30 mL) was added l-fluoro-2,4-dinitrobenzene (1.529 g, 8.22mmol) and Et3N (2.291 mL, 16.44 mmol). The reaction mixture was stirred at 25 C for 12 hr. Progress of the reaction was monitored by TLC (TLC system 50% EtOAc in Hexane, Rf :0.5).The reaction mixture was concentrated under reduced pressure to get crude compound as a pale yellow solid. The crude compound was triturated with diethyl ether and dried to afford tert-butyl 4-(3-((2,4-d trophenyl)amino)propyl)piperazine-l-carboxylate (2.7 g, 6.48 mmol, 79 % yield) as a pale yellow solid. LCMS: m/z (M+H = 410).
373608-48-1, 373608-48-1 tert-Butyl 4-(3-aminopropyl)piperazine-1-carboxylate 17750945, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; BAILEY, James; CHEN, Yao; HURLE, Mark; LEACH, Craig; TURUNEN, Brandon; (103 pag.)WO2018/134731; (2018); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics