109-01-3, 1-Methylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To the ionic liquid [TPA][Pro] (1 mL) was added amine (1-14; Table-1) (1 mmol) and di-tert-butyl dicarbonate (1.2 mmol). The reaction was stirred at room temperature for an appropriate time (Table-1). After completion of the reaction as monitored by TLC, water was added to the reaction mixture and the product was extracted into ethyl acetate (3 ¡Á 20 mL). The combined organic layer was washed with brine solution and concentrated under reduced pressure to give crude product, which was purified over silica gel column to afford corresponding N-tert-butylcarbamate. The ionic liquid [TPA][Pro] in aqueous solution was recovered by removing water under reduced pressure and dried. The recovered ionic liquid was reused for five times without loss of its activity. Finally, all the compounds confirmed by their m.p.?s, IR, 1H NMR, 13C NMR, mass spectral data and elemental analysis wherever needed.
109-01-3 1-Methylpiperazine 53167, apiperazines compound, is more and more widely used in various.
Reference£º
Article; Vijaya Durga; Rambabu; Srinivasa Reddy; Hari Babu; Asian Journal of Chemistry; vol. 29; 6; (2017); p. 1313 – 1316;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics